CDK4 is an essential insulin effector in adipocytes

Insulin resistance is a fundamental pathogenic factor that characterizes various metabolic disorders, including obesity and type 2 diabetes. Adipose tissue contributes to the development of obesity-related insulin resistance through increased release of fatty acids, altered adipokine secretion, and/...

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Publicado en:J Clin Invest
Autores principales: Lagarrigue, Sylviane, Lopez-Mejia, Isabel C., Denechaud, Pierre-Damien, Escoté, Xavier, Castillo-Armengol, Judit, Jimenez, Veronica, Chavey, Carine, Giralt, Albert, Lai, Qiuwen, Zhang, Lianjun, Martinez-Carreres, Laia, Delacuisine, Brigitte, Annicotte, Jean-Sébastien, Blanchet, Emilie, Huré, Sébastien, Abella, Anna, Tinahones, Francisco J., Vendrell, Joan, Dubus, Pierre, Bosch, Fatima, Kahn, C. Ronald, Fajas, Lluis
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Clinical Investigation 2015
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4701556/
https://ncbi.nlm.nih.gov/pubmed/26657864
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI81480
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