E2F1 promotes hepatic gluconeogenesis and contributes to hyperglycemia during diabetes

OBJECTIVE: Aberrant hepatic glucose production contributes to the development of hyperglycemia and is a hallmark of type 2 diabetes. In a recent study, we showed that the transcription factor E2F1, a component of the cell cycle machinery, contributes to hepatic steatosis through the transcriptional...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: Giralt, Albert, Denechaud, Pierre-Damien, Lopez-Mejia, Isabel C., Delacuisine, Brigitte, Blanchet, Emilie, Bonner, Caroline, Pattou, Francois, Annicotte, Jean-Sébastien, Fajas, Lluis
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6001358/
https://ncbi.nlm.nih.gov/pubmed/29526568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2018.02.011
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