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KRAS and PIK3CA bi-mutations predict a poor prognosis in colorectal cancer patients: A single-site report
STUDY RATIONALE: The coexistence of KRAS and PIK3CA mutations in cells implies potential synergistic hyperactivation of the Ras/MAPK and PI3K/Akt oncogenic pathways. Therefore, it is desirable to investigate the concomitant mutations of KRAS and PIK3CA in colorectal cancer (CRC) samples and whether...
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| Publicado no: | Transl Oncol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Neoplasia Press
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7502368/ https://ncbi.nlm.nih.gov/pubmed/32947236 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100874 |
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