KRAS and PIK3CA bi-mutations predict a poor prognosis in colorectal cancer patients: A single-site report

STUDY RATIONALE: The coexistence of KRAS and PIK3CA mutations in cells implies potential synergistic hyperactivation of the Ras/MAPK and PI3K/Akt oncogenic pathways. Therefore, it is desirable to investigate the concomitant mutations of KRAS and PIK3CA in colorectal cancer (CRC) samples and whether...

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Detaylı Bibliyografya
Yayımlandı:Transl Oncol
Asıl Yazarlar: Luo, Qianxin, Chen, Dianke, Fan, Xinjuan, Fu, Xinhui, Ma, Tenghui, Chen, Daici
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Neoplasia Press 2020
Konular:
Original article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC7502368/
https://ncbi.nlm.nih.gov/pubmed/32947236
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tranon.2020.100874
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