The Spectrum, Tendency and Predictive Value of PIK3CA Mutation in Chinese Colorectal Cancer Patients

BACKGROUND: PIK3CA is a high-frequency mutation gene in colorectal cancer, while its prognostic value remains unclear. This study evaluated the mutation tendency, spectrum, prognosis power and predictive power in cetuximab treatment of PIK3CA in Chinese CRC cohort. METHODS: The PIK3CA exon 9 and 20...

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Bibliografiske detaljer
Udgivet i:Front Oncol
Main Authors: Fu, Xinhui, Lin, Hanjie, Fan, Xinjuan, Zhu, Yaxi, Wang, Chao, Chen, Zhiting, Tan, Xiaoli, Huang, Jinglin, Cai, Yacheng, Huang, Yan
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2021
Fag:
Oncology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032977/
https://ncbi.nlm.nih.gov/pubmed/33842311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.595675
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