The Spectrum, Tendency and Predictive Value of PIK3CA Mutation in Chinese Colorectal Cancer Patients

BACKGROUND: PIK3CA is a high-frequency mutation gene in colorectal cancer, while its prognostic value remains unclear. This study evaluated the mutation tendency, spectrum, prognosis power and predictive power in cetuximab treatment of PIK3CA in Chinese CRC cohort. METHODS: The PIK3CA exon 9 and 20...

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Detalles Bibliográficos
Publicado en:Front Oncol
Main Authors: Fu, Xinhui, Lin, Hanjie, Fan, Xinjuan, Zhu, Yaxi, Wang, Chao, Chen, Zhiting, Tan, Xiaoli, Huang, Jinglin, Cai, Yacheng, Huang, Yan
Formato: Artigo
Idioma:Inglês
Publicado: Frontiers Media S.A. 2021
Assuntos:
Oncology
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC8032977/
https://ncbi.nlm.nih.gov/pubmed/33842311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fonc.2021.595675
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