Abnormal Brain Development in Huntington’ Disease Is Recapitulated in the zQ175 Knock-In Mouse Model

Emerging cellular and molecular studies are providing compelling evidence that altered brain development contributes to the pathogenesis of Huntington’s disease (HD). There has been lacking longitudinal system-level data obtained from in vivo HD models supporting this hypothesis. Our human MRI study...

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Veröffentlicht in:Cereb Cortex Commun
Hauptverfasser: Zhang, Chuangchuang, Wu, Qian, Liu, Hongshuai, Cheng, Liam, Hou, Zhipeng, Mori, Susumu, Hua, Jun, Ross, Christopher A, Zhang, Jiangyang, Nopoulos, Peggy C, Duan, Wenzhen
Format: Artigo
Sprache:Inglês
Veröffentlicht: Oxford University Press 2020
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7501464/
https://ncbi.nlm.nih.gov/pubmed/32984817
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/texcom/tgaa044
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