Ca(2+) Release via IP(3) Receptors Shapes the Cardiac Ca(2+) Transient for Hypertrophic Signaling

Calcium (Ca(2+)) plays a central role in mediating both contractile function and hypertrophic signaling in ventricular cardiomyocytes. L-type Ca(2+) channels trigger release of Ca(2+) from ryanodine receptors for cellular contraction, whereas signaling downstream of G-protein-coupled receptors stimu...

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Bibliographic Details
Published in:Biophys J
Main Authors: Hunt, Hilary, Tilūnaitė, Agnė, Bass, Greg, Soeller, Christian, Roderick, H. Llewelyn, Rajagopal, Vijay, Crampin, Edmund J.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2020
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Articles
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7499065/
https://ncbi.nlm.nih.gov/pubmed/32871099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2020.08.001
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