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Modeling Hypertrophic IP3 Transients in the Cardiac Myocyte

Cardiac hypertrophy is a known risk factor for heart disease, and at the cellular level is caused by a complex interaction of signal transduction pathways. The IP3-calcineurin pathway plays an important role in stimulating the transcription factor NFAT which binds to DNA cooperatively with other hyp...

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Detalhes bibliográficos
Main Authors: Cooling, Michael, Hunter, Peter, Crampin, Edmund J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2072074/
https://ncbi.nlm.nih.gov/pubmed/17693463
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1529/biophysj.107.110031
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