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Sensitivity of NFAT Cycling to Cytosolic Calcium Concentration: Implications for Hypertrophic Signals in Cardiac Myocytes

The nuclear factor of activated T-cell (NFAT) transcription factors play an important role in many biological processes, including pathological cardiac hypertrophy. Stimulated by calcium signals, NFAT is translocated to the nucleus where it can regulate hypertrophic genes (excitation-transcription c...

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Detalhes bibliográficos
Main Authors: Cooling, Michael T., Hunter, Peter, Crampin, Edmund J.
Formato: Artigo
Idioma:Inglês
Publicado em: The Biophysical Society 2009
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2717350/
https://ncbi.nlm.nih.gov/pubmed/19289036
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2008.11.064
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