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Assessing Cardiomyocyte Excitation-Contraction Coupling Site Detection From Live Cell Imaging Using a Structurally-Realistic Computational Model of Calcium Release

Calcium signaling plays a pivotal role in cardiomyocytes, coupling electrical excitation to mechanical contraction of the heart. Determining locations of active calcium release sites, and how their recruitment changes in response to stimuli and in disease states is therefore of central interest in c...

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Foilsithe in:Front Physiol
Main Authors: Ladd, David, Tilūnaitė, Agnė, Roderick, H. Llewelyn, Soeller, Christian, Crampin, Edmund J., Rajagopal, Vijay
Formáid: Artigo
Teanga:Inglês
Foilsithe: Frontiers Media S.A. 2019
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6783691/
https://ncbi.nlm.nih.gov/pubmed/31632297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01263
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