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The physiological roles of tau and Aβ: implications for Alzheimer’s disease pathology and therapeutics

Tau and amyloid beta (Aβ) are the prime suspects for driving pathology in Alzheimer’s disease (AD) and, as such, have become the focus of therapeutic development. Recent research, however, shows that these proteins have been highly conserved throughout evolution and may have crucial, physiological r...

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Библиографические подробности
Опубликовано в: :Acta Neuropathol
Главные авторы: Kent, Sarah A., Spires-Jones, Tara L., Durrant, Claire S.
Формат: Artigo
Язык:Inglês
Опубликовано: Springer Berlin Heidelberg 2020
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498448/
https://ncbi.nlm.nih.gov/pubmed/32728795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02196-w
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