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The physiological roles of tau and Aβ: implications for Alzheimer’s disease pathology and therapeutics

Tau and amyloid beta (Aβ) are the prime suspects for driving pathology in Alzheimer’s disease (AD) and, as such, have become the focus of therapeutic development. Recent research, however, shows that these proteins have been highly conserved throughout evolution and may have crucial, physiological r...

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Detalhes bibliográficos
Publicado no:Acta Neuropathol
Main Authors: Kent, Sarah A., Spires-Jones, Tara L., Durrant, Claire S.
Formato: Artigo
Idioma:Inglês
Publicado em: Springer Berlin Heidelberg 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498448/
https://ncbi.nlm.nih.gov/pubmed/32728795
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00401-020-02196-w
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