NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest

Nuclear factor erythroid 2-related factor 2 (NRF2) is a well-characterized transcription factor that protects cells against oxidative and electrophilic stresses. Emerging evidence has suggested that NRF2 protects cells against DNA damage by mechanisms other than antioxidation, yet the mechanism rema...

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Bibliographic Details
Published in:Nucleic Acids Res
Main Authors: Sun, Xiaohui, Wang, Yan, Ji, Kaihua, Liu, Yang, Kong, Yangyang, Nie, Shasha, Li, Na, Hao, Jianxiu, Xie, Yi, Xu, Chang, Du, Liqing, Liu, Qiang
Format: Artigo
Language:Inglês
Published: Oxford University Press 2020
Subjects:
Genome Integrity, Repair and Replication
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498319/
https://ncbi.nlm.nih.gov/pubmed/32729622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa631
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