NRF2 preserves genomic integrity by facilitating ATR activation and G2 cell cycle arrest

Nuclear factor erythroid 2-related factor 2 (NRF2) is a well-characterized transcription factor that protects cells against oxidative and electrophilic stresses. Emerging evidence has suggested that NRF2 protects cells against DNA damage by mechanisms other than antioxidation, yet the mechanism rema...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Sun, Xiaohui, Wang, Yan, Ji, Kaihua, Liu, Yang, Kong, Yangyang, Nie, Shasha, Li, Na, Hao, Jianxiu, Xie, Yi, Xu, Chang, Du, Liqing, Liu, Qiang
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2020
Assuntos:
Genome Integrity, Repair and Replication
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7498319/
https://ncbi.nlm.nih.gov/pubmed/32729622
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkaa631
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