[(18)F]AZD2461, an Insight on Difference in PARP Binding Profiles for DNA Damage Response PET Imaging

BACKGROUND: Poly (ADP-ribose) polymerase (PARP) inhibitors are extensively studied and used as anti-cancer drugs, as single agents or in combination with other therapies. Most radiotracers developed to date have been chosen on the basis of strong PARP1–3 affinity. Herein, we propose to study AZD2461...

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Bibliographic Details
Published in:Mol Imaging Biol
Main Authors: Guibbal, Florian, Hopkins, Samantha L., Pacelli, Anna, Isenegger, Patrick G., Mosley, Michael, Torres, Julia Baguña, Dias, Gemma M., Mahaut, Damien, Hueting, Rebekka, Gouverneur, Véronique, Cornelissen, Bart
Format: Artigo
Language:Inglês
Published: Springer International Publishing 2020
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497465/
https://ncbi.nlm.nih.gov/pubmed/32342268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-020-01497-6
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