PET Imaging of PARP Expression Using (18)F-Olaparib

Poly(ADP-ribose) polymerase (PARP) inhibitors are increasingly being studied as cancer drugs, as single agents, or as a part of combination therapies. Imaging of PARP using a radiolabeled inhibitor has been proposed for patient selection, outcome prediction, dose optimization, genotoxic therapy eval...

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Bibliographische Detailangaben
Veröffentlicht in:J Nucl Med
Hauptverfasser: Wilson, Thomas C., Xavier, Mary-Ann, Knight, James, Verhoog, Stefan, Torres, Julia Baguña, Mosley, Michael, Hopkins, Samantha L., Wallington, Sheena, Allen, Phillip D., Kersemans, Veerle, Hueting, Rebekka, Smart, Sean, Gouverneur, Véronique, Cornelissen, Bart
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society of Nuclear Medicine 2019
Schlagworte:
Oncology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6448459/
https://ncbi.nlm.nih.gov/pubmed/30389822
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2967/jnumed.118.213223
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