Hypoxia Imaging Using PET and SPECT: The Effects of Anesthetic and Carrier Gas on [(64)Cu]-ATSM, [(99m)Tc]-HL91 and [(18)F]-FMISO Tumor Hypoxia Accumulation

BACKGROUND: Preclinical imaging requires anaesthesia to reduce motion-related artefacts. For direct translational relevance, anaesthesia must not significantly alter experimental outcome. This study reports on the effects of both anaesthetic and carrier gas upon the uptake of [(64)Cu]-CuATSM, [(99m)...

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Hauptverfasser: Kersemans, Veerle, Cornelissen, Bart, Hueting, Rebekka, Tredwell, Matthew, Hussien, Kamila, Allen, Philip D., Falzone, Nadia, Hill, Sally A., Dilworth, Jonathan R., Gouverneur, Veronique, Muschel, Ruth J., Smart, Sean C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2011
Schlagworte:
Research Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3216951/
https://ncbi.nlm.nih.gov/pubmed/22102855
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0025911
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