[(18)F]AZD2461, an Insight on Difference in PARP Binding Profiles for DNA Damage Response PET Imaging

BACKGROUND: Poly (ADP-ribose) polymerase (PARP) inhibitors are extensively studied and used as anti-cancer drugs, as single agents or in combination with other therapies. Most radiotracers developed to date have been chosen on the basis of strong PARP1–3 affinity. Herein, we propose to study AZD2461...

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Detalhes bibliográficos
Publicado no:Mol Imaging Biol
Main Authors: Guibbal, Florian, Hopkins, Samantha L., Pacelli, Anna, Isenegger, Patrick G., Mosley, Michael, Torres, Julia Baguña, Dias, Gemma M., Mahaut, Damien, Hueting, Rebekka, Gouverneur, Véronique, Cornelissen, Bart
Formato: Artigo
Idioma:Inglês
Publicado em: Springer International Publishing 2020
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497465/
https://ncbi.nlm.nih.gov/pubmed/32342268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-020-01497-6
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