[(18)F]AZD2461, an Insight on Difference in PARP Binding Profiles for DNA Damage Response PET Imaging

BACKGROUND: Poly (ADP-ribose) polymerase (PARP) inhibitors are extensively studied and used as anti-cancer drugs, as single agents or in combination with other therapies. Most radiotracers developed to date have been chosen on the basis of strong PARP1–3 affinity. Herein, we propose to study AZD2461...

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Publicat a:Mol Imaging Biol
Autors principals: Guibbal, Florian, Hopkins, Samantha L., Pacelli, Anna, Isenegger, Patrick G., Mosley, Michael, Torres, Julia Baguña, Dias, Gemma M., Mahaut, Damien, Hueting, Rebekka, Gouverneur, Véronique, Cornelissen, Bart
Format: Artigo
Idioma:Inglês
Publicat: Springer International Publishing 2020
Matèries:
Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7497465/
https://ncbi.nlm.nih.gov/pubmed/32342268
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-020-01497-6
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