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CDK7 inhibitors as anticancer drugs
Cyclin-dependent kinase 7 (CDK7), along with cyclin H and MAT1, forms the CDK-activating complex (CAK), which directs progression through the cell cycle via T-loop phosphorylation of cell cycle CDKs. CAK is also a component of the general transcription factor, TFIIH. CDK7-mediated phosphorylation of...
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| Publicado no: | Cancer Metastasis Rev |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2020
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7497306/ https://ncbi.nlm.nih.gov/pubmed/32385714 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10555-020-09885-8 |
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