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On‐Chip Neo‐Glycopeptide Synthesis for Multivalent Glycan Presentation

Single glycan–protein interactions are often weak, such that glycan binding partners commonly utilize multiple, spatially defined binding sites to enhance binding avidity and specificity. Current array technologies usually neglect defined multivalent display. Laser‐based array synthesis technology a...

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Detalhes bibliográficos
Publicado no:Chemistry
Main Authors: Mende, Marco, Tsouka, Alexandra, Heidepriem, Jasmin, Paris, Grigori, Mattes, Daniela S., Eickelmann, Stephan, Bordoni, Vittorio, Wawrzinek, Robert, Fuchsberger, Felix F., Seeberger, Peter H., Rademacher, Christoph, Delbianco, Martina, Mallagaray, Alvaro, Loeffler, Felix F.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496964/
https://ncbi.nlm.nih.gov/pubmed/32315099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202001291
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