On‐Chip Neo‐Glycopeptide Synthesis for Multivalent Glycan Presentation

Single glycan–protein interactions are often weak, such that glycan binding partners commonly utilize multiple, spatially defined binding sites to enhance binding avidity and specificity. Current array technologies usually neglect defined multivalent display. Laser‐based array synthesis technology a...

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Pubblicato in:Chemistry
Autori principali: Mende, Marco, Tsouka, Alexandra, Heidepriem, Jasmin, Paris, Grigori, Mattes, Daniela S., Eickelmann, Stephan, Bordoni, Vittorio, Wawrzinek, Robert, Fuchsberger, Felix F., Seeberger, Peter H., Rademacher, Christoph, Delbianco, Martina, Mallagaray, Alvaro, Loeffler, Felix F.
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496964/
https://ncbi.nlm.nih.gov/pubmed/32315099
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.202001291
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