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Synthetic Multivalent V3 Glycopeptides Display Enhanced Recognition by Glycan-Dependent HIV-1 Broadly Neutralizing Antibodies
We describe here the synthesis of novel multivalent HIV V3 domain glycopeptides and their binding to broadly neutralizing antibodies PGT128 and 10-1074. Our binding data reveal a distinct mode of antigen recognition by the two antibodies and further suggest that multivalent glycopeptides could mimic...
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| 出版年: | Chem Commun (Camb) |
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| 主要な著者: | , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
2017
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5518472/ https://ncbi.nlm.nih.gov/pubmed/28466900 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c7cc02059g |
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