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Multivalent Antigen Presentation Enhances the Immunogenicity of a Synthetic Three-Component HIV-1 V3 Glycopeptide Vaccine
[Image: see text] HIV-1 envelope glycoproteins gp120 and gp41 are presented on the virus surface as a trimer of heterodimer and are the targets of broadly neutralizing antibodies (bNAbs). We describe here the synthesis and preliminary immunological evaluation of a three-component trivalent HIV-1 V3...
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| Veröffentlicht in: | ACS Cent Sci |
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| Hauptverfasser: | , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
American Chemical Society
2018
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| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5968512/ https://ncbi.nlm.nih.gov/pubmed/29806004 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acscentsci.8b00060 |
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