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PKA phosphorylation underlies functional recruitment of sarcolemmal SK2 channels in ventricular myocytes from hypertrophic hearts
KEY POINTS: Small‐conductance Ca(2+)‐activated K(+) (SK) channels expressed in ventricular myocytes are dormant in health, yet become functional in cardiac disease. SK channels are voltage independent and their gating is controlled by intracellular [Ca(2+)] in a biphasic manner. Submicromolar [Ca(2+...
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| 出版年: | J Physiol |
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| 主要な著者: | , , , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
John Wiley and Sons Inc.
2019
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7496687/ https://ncbi.nlm.nih.gov/pubmed/30771223 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/JP277618 |
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