Base and Covariate Population Pharmacokinetic Analyses of Dupilumab Using Phase 3 Data

Population pharmacokinetic base and covariate models were developed to study functional dupilumab for regulatory submissions, using data from healthy volunteers and patients with moderate‐to‐severe atopic dermatitis (AD) receiving intravenous or subcutaneous doses. Sixteen studies were pooled (N = 2...

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Foilsithe in:Clin Pharmacol Drug Dev
Main Authors: Kovalenko, Pavel, Davis, John D., Li, Meng, Rippley, Ronda, Ardeleanu, Marius, Shumel, Brad, Graham, Neil M.H., Pirozzi, Gianluca, Kamal, Mohamed A., DiCioccio, A. Thomas
Formáid: Artigo
Teanga:Inglês
Foilsithe: John Wiley and Sons Inc. 2020
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Articles
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496533/
https://ncbi.nlm.nih.gov/pubmed/32096596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.780
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