Base and Covariate Population Pharmacokinetic Analyses of Dupilumab Using Phase 3 Data

Population pharmacokinetic base and covariate models were developed to study functional dupilumab for regulatory submissions, using data from healthy volunteers and patients with moderate‐to‐severe atopic dermatitis (AD) receiving intravenous or subcutaneous doses. Sixteen studies were pooled (N = 2...

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Bibliografski detalji
Izdano u:Clin Pharmacol Drug Dev
Glavni autori: Kovalenko, Pavel, Davis, John D., Li, Meng, Rippley, Ronda, Ardeleanu, Marius, Shumel, Brad, Graham, Neil M.H., Pirozzi, Gianluca, Kamal, Mohamed A., DiCioccio, A. Thomas
Format: Artigo
Jezik:Inglês
Izdano: John Wiley and Sons Inc. 2020
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Articles
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496533/
https://ncbi.nlm.nih.gov/pubmed/32096596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.780
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