Base and Covariate Population Pharmacokinetic Analyses of Dupilumab Using Phase 3 Data

Population pharmacokinetic base and covariate models were developed to study functional dupilumab for regulatory submissions, using data from healthy volunteers and patients with moderate‐to‐severe atopic dermatitis (AD) receiving intravenous or subcutaneous doses. Sixteen studies were pooled (N = 2...

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Bibliografiske detaljer
Udgivet i:Clin Pharmacol Drug Dev
Main Authors: Kovalenko, Pavel, Davis, John D., Li, Meng, Rippley, Ronda, Ardeleanu, Marius, Shumel, Brad, Graham, Neil M.H., Pirozzi, Gianluca, Kamal, Mohamed A., DiCioccio, A. Thomas
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2020
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Articles
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496533/
https://ncbi.nlm.nih.gov/pubmed/32096596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cpdd.780
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