Structure–property studies of an imidazoquinoline chemotype with antitrypanosomal activity

Human African trypanosomiasis is a neglected tropical disease (NTD) that is fatal if left untreated. Although approximately 13 million people live in moderate- to high-risk areas for infection, current treatments are plagued by problems with safety, efficacy, and emerging resistance. In an effort to...

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Veröffentlicht in:RSC Med Chem
Hauptverfasser: Klug, Dana M., Diaz-Gonzalez, Rosario, DeLano, Travis J., Mavrogiannaki, Eftychia M., Buskes, Melissa J., Dalton, Raeann M., Fisher, John K., Schneider, Katherine M., Hilborne, Vivian, Fritsche, Melanie G., Simpson, Quillon J., Tear, Westley F., Devine, William G., Pérez-Moreno, Guiomar, Ceballos-Pérez, Gloria, García-Hernández, Raquel, Bosch-Navarrete, Cristina, Ruiz-Pérez, Luis Miguel, Gamarro, Francisco, González-Pacanowska, Dolores, Martinez-Martinez, Maria Santos, Manzano-Chinchon, Pilar, Navarro, Miguel, Pollastri, Michael P., Ferrins, Lori
Format: Artigo
Sprache:Inglês
Veröffentlicht: Royal Society of Chemistry 2020
Schlagworte:
Chemistry
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496307/
https://ncbi.nlm.nih.gov/pubmed/33479690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00103a
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