Structure–property studies of an imidazoquinoline chemotype with antitrypanosomal activity

Human African trypanosomiasis is a neglected tropical disease (NTD) that is fatal if left untreated. Although approximately 13 million people live in moderate- to high-risk areas for infection, current treatments are plagued by problems with safety, efficacy, and emerging resistance. In an effort to...

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Detalhes bibliográficos
Publicado no:RSC Med Chem
Main Authors: Klug, Dana M., Diaz-Gonzalez, Rosario, DeLano, Travis J., Mavrogiannaki, Eftychia M., Buskes, Melissa J., Dalton, Raeann M., Fisher, John K., Schneider, Katherine M., Hilborne, Vivian, Fritsche, Melanie G., Simpson, Quillon J., Tear, Westley F., Devine, William G., Pérez-Moreno, Guiomar, Ceballos-Pérez, Gloria, García-Hernández, Raquel, Bosch-Navarrete, Cristina, Ruiz-Pérez, Luis Miguel, Gamarro, Francisco, González-Pacanowska, Dolores, Martinez-Martinez, Maria Santos, Manzano-Chinchon, Pilar, Navarro, Miguel, Pollastri, Michael P., Ferrins, Lori
Formato: Artigo
Idioma:Inglês
Publicado em: Royal Society of Chemistry 2020
Assuntos:
Chemistry
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496307/
https://ncbi.nlm.nih.gov/pubmed/33479690
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/d0md00103a
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