Evaluation of a class of isatinoids identified from a high-throughput screen of human kinase inhibitors as anti-Sleeping Sickness agents

New treatments are needed for neglected tropical diseases (NTDs) such as Human African trypanosomiasis (HAT), Chagas disease, and schistosomiasis. Through a whole organism high-throughput screening campaign, we previously identified 797 human kinase inhibitors that grouped into 59 structural cluster...

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Detalhes bibliográficos
Publicado no:PLoS Negl Trop Dis
Main Authors: Klug, Dana M., Diaz-Gonzalez, Rosario, Pérez-Moreno, Guiomar, Ceballos-Pérez, Gloria, García-Hernández, Raquel, Gomez-Pérez, Veronica, Ruiz-Pérez, Luis Miguel, Rojas-Barros, Domingo I., Gamarro, Francisco, González-Pacanowska, Dolores, Martínez-Martínez, María S., Manzano, Pilar, Ferrins, Lori, Caffrey, Conor R., Navarro, Miguel, Pollastri, Michael P.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6383948/
https://ncbi.nlm.nih.gov/pubmed/30735501
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0007129
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