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Potential of ileal bile acid transporter inhibition as a therapeutic target in Alagille syndrome and progressive familial intrahepatic cholestasis

Alagille syndrome (ALGS) and progressive familial intrahepatic cholestasis (PFIC) are rare, inherited cholestatic liver disorders that manifest in infants and children and are associated with impaired bile flow (ie cholestasis), pruritus and potentially fatal liver disease. There are no effective or...

詳細記述

保存先:
書誌詳細
出版年:Liver Int
主要な著者: Kamath, Binita M., Stein, Philip, Houwen, Roderick H. J., Verkade, Henkjan J.
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2020
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496162/
https://ncbi.nlm.nih.gov/pubmed/32492754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14553
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