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Potential of ileal bile acid transporter inhibition as a therapeutic target in Alagille syndrome and progressive familial intrahepatic cholestasis

Alagille syndrome (ALGS) and progressive familial intrahepatic cholestasis (PFIC) are rare, inherited cholestatic liver disorders that manifest in infants and children and are associated with impaired bile flow (ie cholestasis), pruritus and potentially fatal liver disease. There are no effective or...

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Détails bibliographiques
Publié dans:Liver Int
Auteurs principaux: Kamath, Binita M., Stein, Philip, Houwen, Roderick H. J., Verkade, Henkjan J.
Format: Artigo
Langue:Inglês
Publié: John Wiley and Sons Inc. 2020
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496162/
https://ncbi.nlm.nih.gov/pubmed/32492754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14553
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