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Potential of ileal bile acid transporter inhibition as a therapeutic target in Alagille syndrome and progressive familial intrahepatic cholestasis

Alagille syndrome (ALGS) and progressive familial intrahepatic cholestasis (PFIC) are rare, inherited cholestatic liver disorders that manifest in infants and children and are associated with impaired bile flow (ie cholestasis), pruritus and potentially fatal liver disease. There are no effective or...

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Detalhes bibliográficos
Publicado no:Liver Int
Main Authors: Kamath, Binita M., Stein, Philip, Houwen, Roderick H. J., Verkade, Henkjan J.
Formato: Artigo
Idioma:Inglês
Publicado em: John Wiley and Sons Inc. 2020
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496162/
https://ncbi.nlm.nih.gov/pubmed/32492754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14553
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