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Potential of ileal bile acid transporter inhibition as a therapeutic target in Alagille syndrome and progressive familial intrahepatic cholestasis

Alagille syndrome (ALGS) and progressive familial intrahepatic cholestasis (PFIC) are rare, inherited cholestatic liver disorders that manifest in infants and children and are associated with impaired bile flow (ie cholestasis), pruritus and potentially fatal liver disease. There are no effective or...

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Bibliografische gegevens
Gepubliceerd in:Liver Int
Hoofdauteurs: Kamath, Binita M., Stein, Philip, Houwen, Roderick H. J., Verkade, Henkjan J.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: John Wiley and Sons Inc. 2020
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496162/
https://ncbi.nlm.nih.gov/pubmed/32492754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/liv.14553
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