Small‐Molecule Inhibitors Targeting Sterol 14α‐Demethylase (CYP51): Synthesis, Molecular Modelling and Evaluation Against Candida albicans

Fungal infections are a global issue affecting over 150 million people worldwide annually, with 750 000 of these caused by invasive Candida infections. Azole drugs are the frontline treatment against fungal infections; however, resistance to current azole antifungals in C. albicans poses a threat to...

Descrizione completa

Salvato in:
Dettagli Bibliografici
Pubblicato in:ChemMedChem
Autori principali: Binjubair, Faizah A., Parker, Josie E., Warrilow, Andrew G., Puri, Kalika, Braidley, Peter J., Tatar, Esra, Kelly, Steven L., Kelly, Diane E., Simons, Claire
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2020
Soggetti:
Full Papers
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7496091/
https://ncbi.nlm.nih.gov/pubmed/32459374
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/cmdc.202000250
Tags: Aggiungi Tag
Nessun Tag, puoi essere il primo ad aggiungerne! !

Documenti analoghi