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GPU acceleration of Darwin read overlapper for de novo assembly of long DNA reads

BACKGROUND: In Overlap-Layout-Consensus (OLC) based de novo assembly, all reads must be compared with every other read to find overlaps. This makes the process rather slow and limits the practicality of using de novo assembly methods at a large scale in the field. Darwin is a fast and accurate read...

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Veröffentlicht in:BMC Bioinformatics
Hauptverfasser: Ahmed, Nauman, Qiu, Tong Dong, Bertels, Koen, Al-Ars, Zaid
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2020
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7495891/
https://ncbi.nlm.nih.gov/pubmed/32938392
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12859-020-03685-1
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