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Molecular Origins of APOBEC-Associated Mutations in Cancer
The APOBEC family of cytidine deaminases has been proposed to represent a major enzymatic source of mutations in cancer. Here, we summarize available evidence that links APOBEC deaminases to cancer mutagenesis. We also highlight newly identified human cell models of APOBEC mutagenesis, including can...
Tallennettuna:
| Julkaisussa: | DNA Repair (Amst) |
|---|---|
| Päätekijät: | , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2020
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| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7494591/ https://ncbi.nlm.nih.gov/pubmed/32818816 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.dnarep.2020.102905 |
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