Mutations in the HPV16 genome induced by APOBEC3 are associated with viral clearance

HPV16 causes half of cervical cancers worldwide; for unknown reasons, most infections resolve within two years. Here, we analyze the viral genomes of 5,328 HPV16-positive case-control samples to investigate mutational signatures and the role of human APOBEC3-induced mutations in viral clearance and...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Gepubliceerd in:Nat Commun
Hoofdauteurs: Zhu, Bin, Xiao, Yanzi, Yeager, Meredith, Clifford, Gary, Wentzensen, Nicolas, Cullen, Michael, Boland, Joseph F., Bass, Sara, Steinberg, Mia K., Raine-Bennett, Tina, Lee, DongHyuk, Burk, Robert D., Pinheiro, Maisa, Song, Lei, Dean, Michael, Nelson, Chase W., Burdett, Laurie, Yu, Kai, Roberson, David, Lorey, Thomas, Franceschi, Silvia, Castle, Philip E., Walker, Joan, Zuna, Rosemary, Schiffman, Mark, Mirabello, Lisa
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Nature Publishing Group UK 2020
Onderwerpen:
Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC7021686/
https://ncbi.nlm.nih.gov/pubmed/32060290
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-020-14730-1
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!

Gelijkaardige items