HPV16 E7 Genetic Conservation Is Critical to Carcinogenesis

Although most cervical human papillomavirus type 16 (HPV16) infections become undetectable within 1–2 years, persistent HPV16 causes half of all cervical cancers. We used a novel HPV whole-genome sequencing technique to evaluate an exceptionally large collection of 5,570 HPV16-infected case-control...

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Publicado no:Cell
Main Authors: Mirabello, Lisa, Yeager, Meredith, Yu, Kai, Clifford, Gary M., Xiao, Yanzi, Zhu, Bin, Cullen, Michael, Boland, Joseph F., Wentzensen, Nicolas, Nelson, Chase W., Raine-Bennett, Tina, Chen, Zigui, Bass, Sara, Song, Lei, Yang, Qi, Steinberg, Mia, Burdett, Laurie, Dean, Michael, Roberson, David, Mitchell, Jason, Lorey, Thomas, Franceschi, Silvia, Castle, Philip E., Walker, Joan, Zuna, Rosemary, Kreimer, Aimée R., Beachler, Daniel C., Hildesheim, Allan, Gonzalez, Paula, Porras, Carolina, Burk, Robert D., Schiffman, Mark
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674785/
https://ncbi.nlm.nih.gov/pubmed/28886384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.08.001
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