HPV16 E7 Genetic Conservation Is Critical to Carcinogenesis

Although most cervical human papillomavirus type 16 (HPV16) infections become undetectable within 1–2 years, persistent HPV16 causes half of all cervical cancers. We used a novel HPV whole-genome sequencing technique to evaluate an exceptionally large collection of 5,570 HPV16-infected case-control...

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Détails bibliographiques
Publié dans:Cell
Auteurs principaux: Mirabello, Lisa, Yeager, Meredith, Yu, Kai, Clifford, Gary M., Xiao, Yanzi, Zhu, Bin, Cullen, Michael, Boland, Joseph F., Wentzensen, Nicolas, Nelson, Chase W., Raine-Bennett, Tina, Chen, Zigui, Bass, Sara, Song, Lei, Yang, Qi, Steinberg, Mia, Burdett, Laurie, Dean, Michael, Roberson, David, Mitchell, Jason, Lorey, Thomas, Franceschi, Silvia, Castle, Philip E., Walker, Joan, Zuna, Rosemary, Kreimer, Aimée R., Beachler, Daniel C., Hildesheim, Allan, Gonzalez, Paula, Porras, Carolina, Burk, Robert D., Schiffman, Mark
Format: Artigo
Langue:Inglês
Publié: 2017
Sujets:
Article
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5674785/
https://ncbi.nlm.nih.gov/pubmed/28886384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2017.08.001
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