R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth

R-spondin2 (RSPO2) is a member of the R-spondin family, which are secreted activators of the WNT/β-catenin (CTNNB1) signaling pathway. In the mouse postnatal ovary, WNT/CTNNB1 signaling is active in the oocyte and in the neighboring supporting cells, the granulosa cells. Although the role of Rspo2 h...

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Pubblicato in:Cell Death Differ
Autori principali: De Cian, Marie-Cécile, Gregoire, Elodie P., Le Rolle, Morgane, Lachambre, Simon, Mondin, Magali, Bell, Sheila, Guigon, Céline J., Chassot, Anne-Amandine, Chaboissier, Marie-Christine
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2020
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493947/
https://ncbi.nlm.nih.gov/pubmed/32341451
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41418-020-0547-7
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