R-spondin1 Controls Muscle Cell Fusion through Dual Regulation of Antagonistic Wnt Signaling Pathways

Wnt-mediated signals are involved in many important steps in mammalian regeneration. In multiple cell types, the R-spondin (Rspo) family of secreted proteins potently activates the canonical Wnt/β-catenin pathway. Here, we identify Rspo1 as a mediator of skeletal muscle tissue repair. First, we show...

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Detalhes bibliográficos
Publicado no:Cell Rep
Main Authors: Lacour, Floriane, Vezin, Elsa, Bentzinger, C. Florian, Sincennes, Marie-Claude, Giordani, Lorenzo, Ferry, Arnaud, Mitchell, Robert, Patel, Ketan, Rudnicki, Michael A., Chaboissier, Marie-Christine, Chassot, Anne-Amandine, Le Grand, Fabien
Formato: Artigo
Idioma:Inglês
Publicado em: Cell Press 2017
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Report
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5357729/
https://ncbi.nlm.nih.gov/pubmed/28273449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2017.02.036
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