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IMP3 accelerates the progression of prostate cancer through inhibiting PTEN expression in a SMURF1-dependent way

BACKGROUND: Insulin-like growth factor 2 (IGF2) messenger RNA binding protein 3 (IMP3) has been testified to be overexpressed in prostate cancer and strongly related to patients’ poor prognosis. However, the functions of IMP3 and the underlying mechanisms in prostate cancer still remain unknown. The...

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Publicat a:J Exp Clin Cancer Res
Autors principals: Zhang, Xiang, Wang, Dawei, Liu, Boke, Jin, Xingwei, Wang, Xianjin, Pan, Junwei, Tu, Weichao, Shao, Yuan
Format: Artigo
Idioma:Inglês
Publicat: BioMed Central 2020
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493339/
https://ncbi.nlm.nih.gov/pubmed/32938489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01657-0
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