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IMP3 accelerates the progression of prostate cancer through inhibiting PTEN expression in a SMURF1-dependent way

BACKGROUND: Insulin-like growth factor 2 (IGF2) messenger RNA binding protein 3 (IMP3) has been testified to be overexpressed in prostate cancer and strongly related to patients’ poor prognosis. However, the functions of IMP3 and the underlying mechanisms in prostate cancer still remain unknown. The...

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Vydáno v:J Exp Clin Cancer Res
Hlavní autoři: Zhang, Xiang, Wang, Dawei, Liu, Boke, Jin, Xingwei, Wang, Xianjin, Pan, Junwei, Tu, Weichao, Shao, Yuan
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2020
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493339/
https://ncbi.nlm.nih.gov/pubmed/32938489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01657-0
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