IMP3 accelerates the progression of prostate cancer through inhibiting PTEN expression in a SMURF1-dependent way

BACKGROUND: Insulin-like growth factor 2 (IGF2) messenger RNA binding protein 3 (IMP3) has been testified to be overexpressed in prostate cancer and strongly related to patients’ poor prognosis. However, the functions of IMP3 and the underlying mechanisms in prostate cancer still remain unknown. The...

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Bibliographic Details
Published in:J Exp Clin Cancer Res
Main Authors: Zhang, Xiang, Wang, Dawei, Liu, Boke, Jin, Xingwei, Wang, Xianjin, Pan, Junwei, Tu, Weichao, Shao, Yuan
Format: Artigo
Language:Inglês
Published: BioMed Central 2020
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Research
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC7493339/
https://ncbi.nlm.nih.gov/pubmed/32938489
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13046-020-01657-0
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