Chemical Profiling of HIV-1 Capsid-Targeting Antiviral PF74

The capsid protein (CA) of HIV-1 plays essential roles in multiple steps of the viral replication cycle by assembling into functional capsid core, controlling the kinetics of uncoating and nuclear entry, and interacting with various host factors. Targeting CA represents an attractive yet underexplor...

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Publicat a:Eur J Med Chem
Autors principals: Wang, Lei, Casey, Mary C., Vernekar, Sanjeev Kumar V., Do, Ha T., Sahani, Rajkumar Lalji, Kirby, Karen A., Du, Haijuan, Hachiya, Atsuko, Zhang, Huanchun, Tedbury, Philip R., Xie, Jiashu, Sarafianos, Stefan G., Wang, Zhengqiang
Format: Artigo
Idioma:Inglês
Publicat: 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7492092/
https://ncbi.nlm.nih.gov/pubmed/32438252
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ejmech.2020.112427
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