Toward Structurally Novel and Metabolically Stable HIV-1 Capsid-Targeting Small Molecules

HIV-1 capsid protein (CA) plays an important role in many steps of viral replication and represents an appealing antiviral target. Several CA-targeting small molecules of various chemotypes have been studied, but the peptidomimetic PF74 has drawn particular interest due to its potent antiviral activ...

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Publicat a:Viruses
Autors principals: Vernekar, Sanjeev Kumar V., Sahani, Rajkumar Lalji, Casey, Mary C., Kankanala, Jayakanth, Wang, Lei, Kirby, Karen A., Du, Haijuan, Zhang, Huanchun, Tedbury, Philip R., Xie, Jiashu, Sarafianos, Stefan G., Wang, Zhengqiang
Format: Artigo
Idioma:Inglês
Publicat: MDPI 2020
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7232165/
https://ncbi.nlm.nih.gov/pubmed/32316297
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/v12040452
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