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Novel Sulfonamide Analogs of Sivelestat as Potent Human Neutrophil Elastase Inhibitors
Human neutrophil elastase (HNE) is involved in a number of essential physiological processes and has been identified as a potential therapeutic target for treating acute and chronic lung injury. Nevertheless, only one drug, Sivelestat, has been approved for clinical use and just in Japan and the Rep...
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| 出版年: | Front Chem |
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| 主要な著者: | , , , , , , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
Frontiers Media S.A.
2020
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7491426/ https://ncbi.nlm.nih.gov/pubmed/33033716 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fchem.2020.00795 |
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