Further modifications of 1H-pyrrolo[2,3-b]pyridine derivatives as inhibitors of human neutrophil elastase

Human neutrophil elastase (HNE) is a potent protease that plays an important physiological role in many processes and is considered to be a multifunctional enzyme. HNE is also involved in a variety of pathologies affecting the respiratory system. Thus, compounds able to inhibit HNE proteolytic activ...

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Bibliografiske detaljer
Udgivet i:Drug Dev Res
Main Authors: Giovannoni, Maria Paola, Cantini, Niccolò, Crocetti, Letizia, Guerrini, Gabriella, Iacovone, Antonella, Schepetkin, Igor A., Vergelli, Claudia, Khlebnikov, Andrei I., Quinn, Mark T.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687522/
https://ncbi.nlm.nih.gov/pubmed/31002441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ddr.21539
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