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Understanding and Improving the Membrane Permeability of VH032-Based PROTACs
[Image: see text] Proteolysis targeting chimeras (PROTACs) are catalytic heterobifunctional molecules that can selectively degrade a protein of interest by recruiting a ubiquitin E3 ligase to the target, leading to its ubiquitylation and degradation by the proteasome. Most degraders lie outside the...
Gorde:
| Argitaratua izan da: | ACS Med Chem Lett |
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| Egile Nagusiak: | , , , , , , , , |
| Formatua: | Artigo |
| Hizkuntza: | Inglês |
| Argitaratua: |
American Chemical
Society
2020
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| Sarrera elektronikoa: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7488288/ https://ncbi.nlm.nih.gov/pubmed/32939229 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.0c00265 |
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